ARTHRITIS
● Types
of arthritis
● Symptoms
of arthritis
● Signs
of arthritis
TYPES OF ARTHRITIS
●
Rheumatoid
arthritis (RA)
●
Osteoarthritis
(OA)
●
Sero-negative
arthritis
●
Ankylosing
spondylitis
●
Reiter’s
disease
●
Crystal
arthropathies
RHEUMATOID ARTHRITIS
●
affects
3% population
●
female>
male (3:1)
●
80%
RF
●
30%
ANF
●
HLA
DR4 (chr 6)
RHEUMATOID ARTHRITIS PATHOLOGY
- Synovitis
- Destruction
proteolytic enzymes, pannus
- Deformity
articular
destruction, capsular stretching, tendon rupture
RHEUMATOID ARTHRITIS EXTRA-ARTICULAR
●
nodules
●
tendon
sheath
●
vasculitis
●
myopathy
and neuropathy
●
reticulo-endothelial
system
●
visceral
- lungs, heart, kidneys, brain, GI
RHEUMATOID ARTHRITIS EARLY SYMPTOMS
● myopathy,
tiredness, weight loss, malaise
●
proximal
finger joints
●
wrists,
feet, knees, shoulders
●
start
up pain
●
tendon
crepitus
RHEUMATOID ARTHRITIS EARLY JOINT CHANGES
RHEUMATOID ARTHRITIS LATE SYMPTOMS
●
joint
destruction
●
pain
●
deformity
●
instability
RHEUMATOID ARTHRITIS ADVANCED JOINT CHANGES
RHEUMATOID ARTHRITIS X-RAY FINDINGS
●
joint
space narrowing
●
peri-articular
osteopenia
●
erosions
RHEUMATOID ARTHRITIS TREATMENT
●
stop
synovitis
●
prevent
deformity
●
reconstruct
●
rehabilitate
RHEUMATOID ARTHRITIS PROGNOSIS
●
10%
improve
●
60%
intermittent, slowly worsening
●
20%
severe joint erosion, multiple surgery
●
10%
completely disabled
OSTEOARTHRITIS
A
chronic joint disorder in which there is progressive softening and
disintegration of articular cartilage accompanied by new growth of cartilage
and bone at the joint margins (osteophytes) and capsular fibrosis
OSTEOARTHRITIS CLASSIFICATION
●
Primary
or idiopathic
●
Secondary
- infection
- dysplasia
- Perthes’
- SUFE
- trauma
- AVN
OSTEOARTHRITIS AETIOLOGY
●
Genetic
●
metabolic
●
hormonal
●
mechanical
●
ageing
OSTEOARTHRITIS X-RAY CHANGES
●
joint
space narrowing
●
subchondral
sclerosis
●
osteophytes
●
cysts
ARTHRITIS SYMPTOMS
●
pain
●
swelling
●
stiffness
●
deformity
●
instability
●
loss
of function
ARTHRITIS NON-SURGICAL TREATMENT
●
analgesia
●
disease
modifying drugs (RA)
●
altered
activity
●
walking
aids
●
physiotherapy
ARTHRITIS SURGICAL TREATMENT
●
arthroscopy
●
osteotomy
●
arthrodesis
●
excision
arthroplasty
●
replacement
arthroplasty
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